![]() ![]() ![]() Hemolysis and rhabdomyolysis reported in many cases in the literature, were demonstrated by elevated serum levels of indirect bilirubin and creatine kinase. The most commonly identified biopsy finding in these cases is acute tubular necrosis, which can occur due to both, ischemic injury and the nephrotoxicity of venom components. Arterial hypotension plays an important role in this type of AKI, leading to ischemic renal lesion. Acute kidney injury (AKI) can be observed in patients suffering from bee stings and this is due to multiple factors, such as intravascular hemolysis, rhabdomyolysis, hypotension and direct toxicity of the venom components to the renal tubules. ![]() The poison components are melitin, apamin, peptide 401, phospholipase A2, hyaluronidase, histamine, dopamine, and norepinephrine, with melitin being the main lethal component. The poisoning effects can be systemic and can eventually cause death. Allergic reactions can be triggered by a single sting and the greater the number of stings, the worse the prognosis. Acute kidney injury complicating bee stings – a reviewĭa Silva, Geraldo Bezerra Vasconcelos, Adolfo Gomes Rocha, Amanda Maria Timbó de Vasconcelos, Vanessa Ribeiro de Barros, João Fujishima, Julye Sampaio Ferreira, Nathália Barros Barros, Elvino José Guardão Daher, Elizabeth De FrancescoĪBSTRACT Bee stings can cause severe reactions and have caused many victims in the last years. ![]()
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